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Department of Reproductive Endocrinology Cavazza Lab

Publications

2023

Mammalian oocytes store proteins for the early embryo on cytoplasmic lattices.

Jentoft IMA, Bäuerlein FJB, Welp LM, Cooper BH, Petrovic A, So C, Penir SM, Politi AZ, Horokhovskyi Y, Takala I, Eckel H, Moltrecht R, Lénárt P, Cavazza T, Liepe J, Brose N, Urlaub H, Fernández-Busnadiego R, and Schuh M

Cell, 2023

 

2022

Stressful start causes chromosome errors in human embryos

Cavazza  T and Schuh M

Nature, 2022

 

Volumetric morphometry reveals mitotic spindle width as the best predictor of spindle scaling.

Kletter T, Reusch S, Cavazza T, Dempewolf T, Tischer C, and Reber S

Journal of Cell Biology,  2022

 

2021

Parental genome unification is highly erroneous in mammalian embryos.

Cavazza T, Takeda Y, Politi AZ, Aushev M, Aldag P, Baker C, Choudhary M, Bucevičius J, Lukinavičius G, Elder K, Blayney M, Lucas-Hahn A, Niemann H, Herbert M, and Schuh M.

Cell, 2021

Covered by Nature Research Highlights on May 2021

 

Two mechanisms drive pronuclear migration in mouse zygotes.

Scheffler K, Uraji J, Jentoft I, Cavazza T, Mönnich E, Mogessie B, and Schuh M

Nature Communications, 2021

 

Human oocyte aneuploidy and meiotic spindle organization.

*Thomas C, *Cavazza T, and Schuh M

Biochemical Society Transactions, 2021

*These authors contributed equally

 

2018

Proteomic profiling of microtubule self-organization in M-phase.

*Rosas-Salvans M, *Cavazza T, Espadas G, Mancuso F, Sabido E, and Vernos I

 Molecular and Cellular Proteomics. 2018

*These authors contributed equally

 

2016

The sequential activation of the mitotic microtubule assembly pathway favours bipolar spindle assembly.

Cavazza T, Malgaretti P, and Vernos I.

Molecular Biology of the Cell, 2016

 

Allosteric inhibition of Aurora-A kinase by a synthetic vNAR domain.

Burgess SG, Oleksy A, Cavazza T, Richards MW, Vernos I, Matthews D, and Bayliss R

Open Biology, 2016

 

From meiosis to mitosis: the sperm centrosome defines the kinetics of spindle assembly after fertilization in Xenopus.

Cavazza T, Peset I, and Vernos I

Journal of Cell Science, 2016

 

The RanGTP pathway: from the nucleo-cytoplasmic transport to spindle assembly and beyond.

Cavazza T and Vernos I

Frontiers in Cell and Developmental Biology, 2016

2015

Aurora-A-dependent control of TACC3 influences the rate of mitotic spindle assembly.

Burgess SG, Peset I, Joseph N, Cavazza T, Vernos I, Pfuhl M, Gergely F, and Bayliss R

PLoS Genetics, 2015

 

2014

XTACC3-XMAP215 association reveals an asymmetric interaction promoting microtubule elongation.

Mortuza GB, Cavazza T, Garcia-Mayoral MF, Hermida D, Peset I, Pedrero JG, Merino N, Blanco FJ, Lyngsø J, Bruix M, Pedersen JS, Vernos I, and Montoya G

Nature Communications, 2014

 

 

2010

High-resolution cryo-electron microscopy structures of murine norovirus 1 and rabbit hemorraagic disease virus reveal marked flexibility in the receptor binding domains.

Katpally U, Voss NR, Cavazza T, Taube S, Rubin JR, Young VL, Stuckey J, Ward VK, Virgin HWT, Wobus CE, and Smith TJ

Journal of Virology, 2010